Western Blot (WB)
(Western blot analysis of extracts from various samples, using STAC3 Antibody. Lane 1: 293 treated with blocking peptide. Lane 2: 293; Lane 3: HUVEC; )
Rabbit STAC3 Polyclonal Antibody | anti-STAC3 antibody
STAC3 Antibody
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Western Blot (WB)
(Western blot analysis of extracts from various samples, using STAC3 Antibody. Lane 1: 293 treated with blocking peptide. Lane 2: 293; Lane 3: HUVEC; )
Western Blot (WB)
(Western blot analysis of extracts from various samples, using STAC3 Antibody. Lane 1: 293 treated with blocking peptide. Lane 2: 293; Lane 3: HUVEC; )
Western Blot (WB)
(Western blot analysis STAC3 using 293 whole cell lysates)
Western Blot (WB)
(Western blot analysis STAC3 using 293 whole cell lysates)
Western Blot (WB)
(Western blot analysis of extracts from mouse brain, using STAC3 Antibody.)
Western Blot (WB)
(Western blot analysis of extracts from mouse brain, using STAC3 Antibody.)
Subunit Structure: Interacts (via SH3 domains) with CACNA1S and CACNA1C (PubMed:29078335). Component of a calcium channel complex with CACNA1S. Component of a calcium channel complex with CACNA1C.
NCBI and Uniprot Product Information
Predicted: 42 kDa
NCBI Description
The protein encoded by this gene is a component of the excitation-contraction coupling machinery of muscles. This protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains. Mutations in this gene are a cause of Native American myopathy. [provided by RefSeq, Nov 2013]
Uniprot Description
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca2+ release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels (PubMed:23736855, PubMed:29078335). Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (). Slows down the inactivation rate of the calcium channel CACNA1C (PubMed:29078335).
Research Articles on STAC3
Similar Products
Product Notes
The STAC3 stac3 (Catalog #AAA9610216) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STAC3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's STAC3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the STAC3 stac3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
