Immunohistochemistry (IHC)
(Human, Lung endothelium: Formalin-Fixed Paraffin-Embedded (FFPE))
Rabbit SS18 / SYT Polyclonal Antibody | anti-SS18 antibody
Rabbit Polyclonal to Human SS18 / SYT
Immunohistochemistry (IHC)
(Human, Lung endothelium: Formalin-Fixed Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human, Lung endothelium: Formalin-Fixed Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot of SYT (A7) pAb in extracts from HepG2 cells.)
Western Blot (WB)
(Western blot of SYT (A7) pAb in extracts from HepG2 cells.)
NCBI and Uniprot Product Information
Uniprot Description
SS18: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SS18 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein; Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 18q11.2
Cellular Component: cytoplasmic microtubule; nucleus
Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity
Biological Process: response to drug; transcription, DNA-dependent; ephrin receptor signaling pathway; cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; microtubule cytoskeleton organization and biogenesis
Research Articles on SS18
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Product Notes
The SS18 ss18 (Catalog #AAA248268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SS18 / SYT reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SS18 / SYT can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the SS18 ss18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SS18 / SYT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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