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Western Blot (WB) (Western blot analysis of extracts of various cells, using SS18 antibody.)

Rabbit anti-Human SS18 Polyclonal Antibody | anti-SS18 antibody

SS18 Polyclonal Antibody

Gene Names
SS18; SYT; SSXT
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SS18; Polyclonal Antibody; SS18 Polyclonal Antibody; SYT; SSXT; anti-SS18 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/ml (varies by lot)
Sequence Length
418
Applicable Applications for anti-SS18 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Immunogen
Recombinant protein of human SS18
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8819 / sc-8820 / sc-32520 / sc-32521 / sc-28698
Preparation and Storage
Store at -20 degree C. Avoid freeze/ thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cells, using SS18 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cells, using SS18 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon carcinoma using SS18 antibody at dilution of 1:200 (40x lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon carcinoma using SS18 antibody at dilution of 1:200 (40x lens).)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,216 Da
NCBI Official Full Name
protein SSXT isoform 1
NCBI Official Synonym Full Names
SS18, nBAF chromatin remodeling complex subunit
NCBI Official Symbol
SS18
NCBI Official Synonym Symbols
SYT; SSXT
NCBI Protein Information
protein SSXT
UniProt Protein Name
Protein SSXT
Protein Family
UniProt Gene Name
SS18
UniProt Synonym Gene Names
SSXT; SYT
UniProt Entry Name
SSXT_HUMAN

Uniprot Description

SS18: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SS18 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: nucleus

Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; protein binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter

Research Articles on SS18

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Product Notes

The SS18 ss18 (Catalog #AAA2540115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SS18 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SS18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:2000 Immunohistochemistry: 1:50 - 1:200. Researchers should empirically determine the suitability of the SS18 ss18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SS18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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