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Western Blot (WB) (Western blot analysis of anti-SNRPD1 Antibody (Center) in HL60 cell line lysates (35ug/lane). SNRPD1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human SNRPD1 Polyclonal Antibody | anti-SNRPD1 antibody

SNRPD1, ID (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (PE)

Gene Names
SNRPD1; SMD1; SNRPD; Sm-D1; HsT2456
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
SNRPD1; Polyclonal Antibody; ID (Small Nuclear Ribonucleoprotein Sm D1; Sm-D1; snRNP Core Protein D1; Sm-D Autoantigen) (PE); anti-SNRPD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SNRPD1.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-SNRPD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the center region of human SNRPD1 (KLH).
Conjugate
PE
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-SNRPD1 Antibody (Center) in HL60 cell line lysates (35ug/lane). SNRPD1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-SNRPD1 Antibody (Center) in HL60 cell line lysates (35ug/lane). SNRPD1 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MASTL Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MASTL Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Western Blot (WB)

(Western blot analysis of SNRPD1 (arrow) using rabbit polyclonal SNRPD1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRPD1 gene.)

Western Blot (WB) (Western blot analysis of SNRPD1 (arrow) using rabbit polyclonal SNRPD1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRPD1 gene.)

Flow Cytometry (FC/FACS)

(SNRPD1 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (SNRPD1 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-SNRPD1 antibody
References
1. Lehner, B., Genome Res. 14(7), 1315-1323 (2004). 2. Will, C.L., RNA 10(6), 929-941 (2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13kDa
NCBI Official Full Name
small nuclear ribonucleoprotein Sm D1 isoform 1
NCBI Official Synonym Full Names
small nuclear ribonucleoprotein D1 polypeptide
NCBI Official Symbol
SNRPD1
NCBI Official Synonym Symbols
SMD1; SNRPD; Sm-D1; HsT2456
NCBI Protein Information
small nuclear ribonucleoprotein Sm D1
UniProt Protein Name
Small nuclear ribonucleoprotein Sm D1
UniProt Gene Name
SNRPD1
UniProt Synonym Gene Names
Sm-D1
UniProt Entry Name
SMD1_HUMAN

NCBI Description

This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot Description

snRNP D1: May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. Belongs to the snRNP core protein family.

Protein type: Spliceosome; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; snRNP U1; cytosol; nucleus; U12-dependent spliceosome

Molecular Function: protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression

Research Articles on SNRPD1

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Product Notes

The SNRPD1 snrpd1 (Catalog #AAA6499997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNRPD1, ID (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SNRPD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SNRPD1 snrpd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNRPD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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