Goat SLC6A8 Polyclonal Antibody | anti-SLC6A8 antibody

Anti-SLC6A8 Antibody (aa212-226)

Cat. Num. AAA2400877

• Gene Names: SLC6A8; CRT; CT1; CRTR; CTR5; CCDS1
• Reactivity: Human; Predicted: Mouse, Dog, Guinea pig, Rat, Hamster, Horse, Bat, Monkey
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: SLC6A8; Polyclonal Antibody; Anti-SLC6A8 Antibody (aa212-226); Rabbit Polyclonal (IgG) to Human SLC6A8; Creatine transporter 1; Creatine transporter SLC6A8; CRTR; CT1; CRT; anti-SLC6A8 antibody

• Host: Goat
• Reactivity: Human; Predicted: Mouse, Dog, Guinea pig, Rat, Hamster, Horse, Bat, Monkey
• Clonality: Polyclonal
• Specificity: Human SLC6A8. This antibody is expected to recognize all reported isoforms (NP_005620.1; NP_001136277.1; NP_001136278.1).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Sequence Length: 635

• Applicable Applications for anti-SLC6A8 antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: ELISA: 1:8000; IHC-P: 5 ug/ml; WB: 0.1-0.3 ug/ml
• Immunogen: Synthetic peptide ASLANLTCDQLADRR from an internal region of human SLC6A8 (NP_005620.1; NP_001136277.1; NP_001136278.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bat, Hamster, Elephant, Panda, Horse, Guinea pig (100%); Orangutan (93%); Bovine, Rabbit (87%); Opossum (80%).
• Conjugation: Unconjugated
• Epitope: aa212-226
• Preparation and Storage: Store at -20 degree C.; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-SLC6A8 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(SLC6A8 antibody (0.1 ug/ml) staining of Mouse Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Related Product Information for anti-SLC6A8 antibody

SLC6A8 is a plasma membrane protein whose function is to transportcreatine into and out of cells. Defects in this gene can result inX-linked creatine deficiency syndrome. Multiple transcript variantsencoding different isoforms have been found for this gene.

Product Categories/Family for anti-SLC6A8 antibody

Transporter; Neurotransmitter:sodium symporter

NCBI and Uniprot Product Information

• NCBI GI #: 5032097
• NCBI GeneID: 6535
• NCBI Accession #: NP_005620.1
• NCBI GenBank Nucleotide #: NM_005629.3
• UniProt Accession #: P48029; Q13032; Q66I36; B2KY47; B4DIA3; E9PFC0
• Molecular Weight: 58,453 Da
• NCBI Official Full Name: sodium- and chloride-dependent creatine transporter 1 isoform 1
• NCBI Official Synonym Full Names: solute carrier family 6 member 8
• NCBI Official Symbol: SLC6A8
• NCBI Official Synonym Symbols: CRT; CT1; CRTR; CTR5; CCDS1
• NCBI Protein Information: sodium- and chloride-dependent creatine transporter 1
• UniProt Protein Name: Sodium- and chloride-dependent creatine transporter 1
• Protein Family: Sodium- and chloride-dependent creatine transporter
• UniProt Gene Name: SLC6A8
• UniProt Synonym Gene Names: CT1; Creatine transporter 1

NCBI Description

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Uniprot Description

Required for the uptake of creatine in muscles and brain.