Immunohistochemistry (IHC)
(Immunochemical staining of human SLC6A18 in human epididymis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SLC6A18 Polyclonal Antibody | anti-SLC6A18 antibody
Anti-SLC6A18 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SLC6A18; Polyclonal Antibody; Anti-SLC6A18 Antibody; Rabbit Polyclonal; SLC6A18 Antibody; Rabbit PAb; Antigen Affinity Purified; solute carrier family 6 (neutral amino acid transporter); member 18; Anti-Xtrp2 Antibody; anti-SLC6A18 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SLC6A18
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SLC6A18 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human SLC6A18 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SLC6A18 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC6A18 in human epididymis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC6A18 in human epididymis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SLC6A18 antibody
SLC6A18 (solute carrier family 6, member 18) acts as a specific transporter for neurotransmitters, amino acids, and osmolytes such as betaine, taurine, and creatine. SLC6A18 is a member of the SLC6 Na(+)-and Cl(-)-dependent neurotransmitter transporter family. The orphan transporter Slc6a18 (XT2) is highly expressed at the luminal membrane of kidney proximal tubules and displays approximately 50% identity with Slc6a19 (B(0)AT1), which is the main neutral amino acid transporter in both the kidney and small intestine. As yet, the amino acid transport function of XT2 has only been experimentally supported by the urinary glycine loss observed in xt2 null mice. Slc6a18 and Slc6a19 have different roles in the intestine, and that both of these contribute to establishing the efficient neutral amino acid absorption system in the tilapia.
References
Singer D, et al. (2009) Orphan transporter slc6a18 is renal neutral amino acid transporter b0at3. J Biol Chem 284 (30): 19953-19960.Orozco ZGA, et al. (2018) Spatial mrna expression and response to fasting and refeeding of neutral amino acid transporters slc6a18 and slc6a19a in the intestinal epithelium of mozambique tilapia. Front Physiol 9 212.Matsumoto K, et al. (2011) Association study: Slc6a18 gene and myocardial infarction. Clin Biochem 44 (10-11): 789-794.
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Product Notes
The SLC6A18 (Catalog #AAA8108620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC6A18 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC6A18 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SLC6A18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC6A18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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