Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A5 in human prostate with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SLC1A5 Polyclonal Antibody | anti-SLC1A5 antibody
Anti-SLC1A5 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SLC1A5; Polyclonal Antibody; Anti-SLC1A5 Antibody; Rabbit Polyclonal; SLC1A5 Antibody; Rabbit PAb; Antigen Affinity Purified; solute carrier family 1 (neutral amino acid transporter); member 5; Anti-AAAT Antibody; Anti-ASCT2 Antibody; Anti-ATBO Antibody; Anti-M7V1 Antibody; Anti-M7VS1 Antibody; Anti-R16 Antibody; Anti-RDRC Antibody; anti-SLC1A5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SLC1A5
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SLC1A5 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human SLC1A5 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SLC1A5 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A5 in human prostate with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A5 in human prostate with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A5 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A5 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SLC1A5 antibody
SLC1A5 (solute carrier family 1, member 5), known as ASCT2, is a small neutral amino acid exchanger that is upregulated in rapidly proliferating lymphocytes but also many primary human cancers. SLC1A5 is a neutral amino acid transporter belonging to the SLC1 family and localized in the plasma membrane of several body districts. Solute-linked carrier family A1 member 5 (SLC1A5), which has a high affinity to neutral amino acids, is essential for glutamine transport and amino acid metabolism in various cancers. One of SLC1A5's primary substrates is the immunomodulatory amino acid glutamine, which plays an important role in multiple key processes, such as energy supply, macromolecular synthesis, nucleotide biosynthesis, redox homeostasis, and resistance against oxidative stress. These processes are also essential to immune cells, including neutrophils, macrophages, B, and T lymphocytes.
References
Scalise M, et al. (2019) Interaction of cholesterol with the human slc1a5 (asct2): Insights into structure/function relationships. Front Mol Biosci 6 110.Scalise M, et al. (2018) The human slc1a5 (asct2) amino acid transporter: From function to structure and role in cell biology. Front Cell Dev Biol 6 96.Masle-Farquhar E, et al. (2017) Asct2 (slc1a5)-deficient mice have normal b-cell development, proliferation, and antibody production. Front Immunol 8 549.Lin J, et al. (2018) Slc1a5 silencing inhibits esophageal cancer growth via cell cycle arrest and apoptosis. Cell Physiol Biochem 48 (1): 397.
Similar Products
Product Notes
The SLC1A5 (Catalog #AAA8108744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC1A5 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC1A5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SLC1A5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC1A5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
