Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A4 in human lymph node with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SLC1A4 Polyclonal Antibody | anti-SLC1A4 antibody
Anti-SLC1A4 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SLC1A4; Polyclonal Antibody; Anti-SLC1A4 Antibody; Rabbit Polyclonal; SLC1A4 Antibody; Rabbit PAb; Antigen Affinity Purified; solute carrier family 1 (glutamate/neutral amino acid transporter); member 4; Anti-ASCT1 Antibody; Anti-SATT Antibody; anti-SLC1A4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SLC1A4
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SLC1A4 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
E Coli-derived Human SLC1A4 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SLC1A4 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A4 in human lymph node with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A4 in human lymph node with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A4 in human adrenal gland with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC1A4 in human adrenal gland with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SLC1A4 antibody
The gene ASCT1 (SLC1A4) coding for a Na+-dependent neutral amino acid transporter is a member of the glutamate transporter superfamily and is located on 2p13-14, a region showing linkage to both schizophrenia (SCZ) and bipolar disorder (BD). ASCT1 can thus be considered a candidate gene for both disorders. SLC1A4 (ASCT1) encodes a transporter for neutral amino acids such as alanine, serine, cysteine, and threonine. Biallelic mutations in the SLC1A4 gene have been identified as a very rare cause of neurodevelopmental disorders. l-serine transport deficiency has been regarded as the causal molecular mechanism underlying the neurological phenotype of SLC1A4 mutation patients. SLC1A4 deficiency is a described neurodevelopmental disorder associated with microcephaly, global developmental delay, abnormal myelination, thin corpus callosum, and seizures.
References
Skowronek MH, et al. (2006) No association between genetic variants at the asct1 gene and schizophrenia or bipolar disorder in a german sample. Psychiatr Genet 16 (6): 233-234.Pironti E, et al. (2018) A novel slc1a4 homozygous mutation causing congenital microcephaly, epileptic encephalopathy and spastic tetraparesis: A video-eeg and tractography-case study. J Neurogenet 32 (4): 316-321.Conroy J, et al. (2016) Novel european slc1a4 variant: Infantile spasms and population ancestry analysis. J Hum Genet 61 (8): 761-764.
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Product Notes
The SLC1A4 (Catalog #AAA8108887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC1A4 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC1A4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the SLC1A4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC1A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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