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Rabbit anti-Human SLC18A1 Polyclonal Antibody | anti-SLC18A1 antibody

SLC18A1 Antibody, Biotin conjugated

Gene Names
SLC18A1; CGAT; VAT1; VMAT1
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
SLC18A1; Polyclonal Antibody; SLC18A1 Antibody; Biotin conjugated; Chromaffin granule amine transporter; Solute carrier family 18 member 1; Vesicular amine transporter 1; VAT1; VMAT1; anti-SLC18A1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
525
Applicable Applications for anti-SLC18A1 antibody
ELISA (EIA)
Immunogen
Recombinant human Chromaffin granule amine transporter protein (66-120AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Biotin
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7718 / sc-7719 / sc-7720 / sc-15313
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-SLC18A1 antibody
Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,677 Da
NCBI Official Full Name
chromaffin granule amine transporter isoform a
NCBI Official Synonym Full Names
solute carrier family 18 member A1
NCBI Official Symbol
SLC18A1
NCBI Official Synonym Symbols
CGAT; VAT1; VMAT1
NCBI Protein Information
chromaffin granule amine transporter
UniProt Protein Name
Chromaffin granule amine transporter
UniProt Gene Name
SLC18A1
UniProt Synonym Gene Names
VAT1; VMAT1; VAT1
UniProt Entry Name
VMAT1_HUMAN

NCBI Description

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC18A1: Involved in the vesicular transport of biogenic amines. Belongs to the major facilitator superfamily. Vesicular transporter family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: integral to plasma membrane; synaptic vesicle membrane; terminal button

Molecular Function: monoamine transmembrane transporter activity; serotonin transmembrane transporter activity

Biological Process: monoamine transport; synaptic transmission; synaptic vesicle amine transport

Research Articles on SLC18A1

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Product Notes

The SLC18A1 slc18a1 (Catalog #AAA7049143) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC18A1 Antibody, Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC18A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the SLC18A1 slc18a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC18A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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