Immunohistochemistry (IHC)
(Immunochemical staining of human SLC16A4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SLC16A4 Polyclonal Antibody | anti-SLC16A4 antibody
Anti-SLC16A4 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SLC16A4; Polyclonal Antibody; Anti-SLC16A4 Antibody; Rabbit Polyclonal; SLC16A4 Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-MCT4 Antibody; Anti-MCT5 Antibody; Anti-RP5-1074L1.3 Antibody; anti-SLC16A4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SLC16A4
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SLC16A4 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human SLC16A4 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SLC16A4 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC16A4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SLC16A4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SLC16A4 antibody
The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and pyruvate, across cell membranes. They are known to play an important role in cell metabolism, such as aerobic glycolysis and pH homeostasis. Currently, 14 gene members named SLC16A1 to SLC16A14 have been identified to have the presence of two highly conserved sequence regions located in TM1 and TM5, respectively, by topology study. MCT1 through MCT4 (MCTs 1-4) are H(+ )-coupled monocarboxylate transporters, MCT8 and MCT10 transport thyroid hormone and aromatic amino acids. SLC16A family members play crucial roles in tumorigenesis and tumor progression.
References
Yu S, et al. (2020) Comprehensive analysis of the slc16a gene family in pancreatic cancer via integrated bioinformatics. Sci Rep 10 (1): 7315.Adijanto J, et al. (2012) The slc16a family of monocarboxylate transporters (mcts)--physiology and function in cellular metabolism, ph homeostasis, and fluid transport. Curr Top Membr 70 275-311.
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Product Notes
The SLC16A4 (Catalog #AAA8109892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC16A4 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC16A4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SLC16A4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC16A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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