Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SIGLEC15 Polyclonal Antibody at dilution 1:35)
Rabbit anti-Human SIGLEC15 Polyclonal Antibody | anti-SIGLEC15 antibody
SIGLEC15 Polyclonal Antibody
Gene Names
SIGLEC15; CD33L3; HsT1361; SIGLEC-15
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity purification
Synonyms
SIGLEC15; Polyclonal Antibody; SIGLEC15 Polyclonal Antibody; G1P2; hUCRP; IFI 15; IFI15; IP17; ISG 15; ISG15; ISG15 ubiquitin like modifier; anti-SIGLEC15 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Sequence Length
328
Applicable Applications for anti-SIGLEC15 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human SIGLEC15
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SIGLEC15 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SIGLEC15 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using SIGLEC15 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using SIGLEC15 Polyclonal Antibody at dilution 1:35)
Related Product Information for anti-SIGLEC15 antibody
Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Sialic acid-binding Ig-like lectin 15
NCBI Official Synonym Full Names
sialic acid binding Ig-like lectin 15
NCBI Official Symbol
SIGLEC15
NCBI Official Synonym Symbols
CD33L3; HsT1361; SIGLEC-15
NCBI Protein Information
sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3; CD33 molecule-like 3
UniProt Protein Name
Sialic acid-binding Ig-like lectin 15
Protein Family
UniProt Gene Name
SIGLEC15
UniProt Synonym Gene Names
CD33L3; Siglec-15
UniProt Entry Name
SIG15_HUMAN
Uniprot Description
CD33L3: Binds sialylated glycoproteins. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 18q12.3
Cellular Component: protein complex; integral to membrane; plasma membrane
Biological Process: regulation of bone resorption; regulation of actin cytoskeleton organization and biogenesis; innate immune response
Research Articles on SIGLEC15
Similar Products
Product Notes
The SIGLEC15 siglec15 (Catalog #AAA2529041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIGLEC15 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIGLEC15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the SIGLEC15 siglec15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIGLEC15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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