Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS6005616. SGSH (arrow) was detected usingMBS6005616.)
Rabbit anti-Human SGSH Polyclonal Antibody | anti-SGSH antibody
SGSH, CT (SGSH, HSS, N-sulphoglucosamine sulphohydrolase, Sulfoglucosamine sulfamidase, Sulphamidase) (MaxLight 650)
Gene Names
SGSH; HSS; SFMD; MPS3A
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
SGSH; Polyclonal Antibody; CT (SGSH; HSS; N-sulphoglucosamine sulphohydrolase; Sulfoglucosamine sulfamidase; Sulphamidase) (MaxLight 650); Sulphamidase; anti-SGSH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SGSH.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-SGSH antibody
FLISA, Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 420-449 in the C-terminal of human SGSH. Cellular Localization: Lysosome UniProt: P51688.
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS6005616. SGSH (arrow) was detected usingMBS6005616.)
Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS6005616. SGSH (arrow) was detected usingMBS6005616.)
Related Product Information for anti-SGSH antibody
SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
Product Categories/Family for anti-SGSH antibody
References
1. Sleat, D.E., et al. Mol. Cell Proteomics 5(4):686-701(2006). 2. Bekri, S., et al. J. Inherit. Metab. Dis. 28(4):601-602(2005). 3. Muschol, N., et al. Hum. Mutat. 23(6):559-566(2004). 4. Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,695 Da
NCBI Official Full Name
N-sulphoglucosamine sulphohydrolase
NCBI Official Synonym Full Names
N-sulfoglucosamine sulfohydrolase
NCBI Official Symbol
SGSH
NCBI Official Synonym Symbols
HSS; SFMD; MPS3A
NCBI Protein Information
N-sulphoglucosamine sulphohydrolase; heparan sulfate sulfatase; mucopolysaccharidosis type IIIA; sulfoglucosamine sulfamidase; sulphamidase
UniProt Protein Name
N-sulphoglucosamine sulphohydrolase
Protein Family
UniProt Gene Name
SGSH
UniProt Synonym Gene Names
HSS
UniProt Entry Name
SPHM_HUMAN
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Product Notes
The SGSH sgsh (Catalog #AAA6347095) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGSH, CT (SGSH, HSS, N-sulphoglucosamine sulphohydrolase, Sulfoglucosamine sulfamidase, Sulphamidase) (MaxLight 650) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SGSH can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SGSH sgsh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGSH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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