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Western Blot (WB) (Western blot analysis of SGLT2 expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)

Rabbit SGLT2 Polyclonal Antibody | anti-SGLT2 antibody

SGLT2 Antibody

Gene Names
SLC5A2; SGLT2
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
SGLT2; Polyclonal Antibody; SGLT2 Antibody; Purified Polyclonal SGLT2 Antibody; Polyclonal SGLT2 antibody; Anti-SGLT2 antibody; SGLT2 antibody; Sodium/glucose cotransporter 2 antibody; Na(+)/glucose cotransporter 2 antibody; Low affinity sodium-glucose cotransporter antibody; Solute carrier family 5 member 2 antibody; anti-SGLT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of SGLT2 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
672
Applicable Applications for anti-SGLT2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
SGLT2 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SGLT2 as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of SGLT2 expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of SGLT2 expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)
Related Product Information for anti-SGLT2 antibody
SGLT2 contributes to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2).
Product Categories/Family for anti-SGLT2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 member 2
NCBI Official Symbol
SLC5A2
NCBI Official Synonym Symbols
SGLT2
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Gene Name
SLC5A2
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2
UniProt Entry Name
SC5A2_HUMAN

NCBI Description

This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]

Uniprot Description

SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: low-affinity glucose:sodium symporter activity

Biological Process: transport; sodium ion transport; carbohydrate metabolic process; glucose transport; transmembrane transport

Disease: Renal Glucosuria

Research Articles on SGLT2

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Product Notes

The SGLT2 slc5a2 (Catalog #AAA5315012) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SGLT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the SGLT2 slc5a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGLT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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