Rabbit Serotonin Receptor 1A Polyclonal Antibody | anti-HTR1A antibody

Serotonin Receptor 1A (5-HT1A)

Cat. Num. AAA611418

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purified ; Purified by affinity chromatography.
• Synonyms: Serotonin Receptor 1A; Polyclonal Antibody; Serotonin Receptor 1A (5-HT1A); Anti -Serotonin Receptor 1A (5-HT1A); anti-HTR1A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes rat Serotonin Receptor 1A. Species Crossreactivity: human and mouse.
• Purity/Purification: Affinity Purified ; Purified by affinity chromatography.
• Form/Format: Supplied as a liquid, 1% BSA.

• Applicable Applications for anti-HTR1A antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot and Immunohistochemistry.; Dilution: Western Blot: Using rat brain extracts of cortex, hypothalamus, midbrain and hindbrain, the antibody specifically labels a single band. Immunolabeling is abolished by pre-adsorption with synthetic rat 5HT transporter (aa579-599).; Immunohistochemistry (indirect IF): 1:200-1:400; Immunohistochemistry (biotin/streptavidin HRP technique): 1:200-1:600 in rat raphe nuclei, hypothalamus, cortex and spinal cord.; Optimal dilution determined by the researcher.
• Immunogen: Synthetic peptide corresponding to aa294-312 of the rat 5-HT1A receptor coupled to bovine thyroglobulin with glutaraldehyde.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-HTR1A antibody

The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

Product Categories/Family for anti-HTR1A antibody

Antibodies; Abs to Serotonin Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 27461808
• NCBI GeneID: 487230
• UniProt Accession #: Q6XXX9
• Molecular Weight: 46,356 Da
• NCBI Official Full Name: serotonin receptor 1A
• NCBI Official Symbol: HTR1A
• NCBI Protein Information: 5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A receptor; serotonin receptor 1A
• UniProt Protein Name: 5-hydroxytryptamine receptor 1A
• Protein Family: 5-hydroxytryptamine receptor
• UniProt Gene Name: HTR1A
• UniProt Entry Name: 5HT1A_CANFA

Uniprot Description

Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.