Western Blot (WB)
(Western blot analysis of mouse anti-Sema5a (N-term) Pab in A2058 cell line lysates (35ug/lane). Sema5a(arrow) was detected using the purified Pab.)
Rabbit anti-Human Sema5a Polyclonal Antibody | anti-SEMA5A antibody
Sema5a, NT (Semaphorin-F, Sema F, Semaphorin-5A, SEMAF, SEMA5A)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Western Blot (WB)
(Western blot analysis of mouse anti-Sema5a (N-term) Pab in A2058 cell line lysates (35ug/lane). Sema5a(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of mouse anti-Sema5a (N-term) Pab in A2058 cell line lysates (35ug/lane). Sema5a(arrow) was detected using the purified Pab.)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.
Uniprot Description
SEMA5A: a single-pass type I membrane protein that may act as positive axonal guidance cues.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p15.2
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: syndecan binding; heparan sulfate proteoglycan binding; axon guidance receptor activity; semaphorin receptor binding
Biological Process: axon guidance; nervous system development; positive regulation of actin filament depolymerization; axonal fasciculation; negative regulation of cell adhesion; negative regulation of axon extension involved in axon guidance; diencephalon development; patterning of blood vessels; positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; blood vessel endothelial cell proliferation during sprouting angiogenesis; cell-cell signaling; positive chemotaxis; positive regulation of axon extension involved in axon guidance; positive regulation of endothelial cell proliferation; cell adhesion
Research Articles on SEMA5A
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Product Notes
The SEMA5A sema5a (Catalog #AAA624625) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Sema5a, NT (Semaphorin-F, Sema F, Semaphorin-5A, SEMAF, SEMA5A) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sema5a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the SEMA5A sema5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sema5a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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