Rabbit anti-Human, Mouse SELK Polyclonal Antibody | anti-SELK antibody

SELK, ID (SELK, Selenoprotein K)

Cat. Num. AAA6001843

• Gene Names: SELK; HSPC030; HSPC297
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SELK; Polyclonal Antibody; ID (SELK; Selenoprotein K); Anti -SELK; anti-SELK antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-SELK antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: SELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the Central region of human SELK.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SELK Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SELK antibody detected the SELK protein (arrow).)

Western Blot (WB)

(SELK Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SELK antibody detected the SELK protein (arrow).)

Related Product Information for anti-SELK antibody

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant.

Product Categories/Family for anti-SELK antibody

Antibodies; Abs to Selenoprotein

NCBI and Uniprot Product Information

• NCBI GI #: 25014099
• NCBI GeneID: 58515
• NCBI Accession #: NP_067060.2
• NCBI GenBank Nucleotide #: NM_021237.3
• UniProt Accession #: Q9Y6D0; Q8IZQ3; Q9P085
• Molecular Weight: 10,645 Da
• NCBI Official Full Name: selenoprotein K
• NCBI Official Symbol: SELK
• NCBI Official Synonym Symbols: HSPC030; HSPC297
• NCBI Protein Information: selenoprotein K
• UniProt Protein Name: Selenoprotein K
• Protein Family: Selenoprotein
• UniProt Gene Name: SELK
• UniProt Synonym Gene Names: SelK
• UniProt Entry Name: SELK_HUMAN

NCBI Description

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. [provided by RefSeq, Jul 2008]

Uniprot Description

SELK: a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; plasma membrane; integral to membrane

Molecular Function: identical protein binding

Biological Process: calcium ion transport; response to oxidative stress