Rabbit anti-Human SELV Polyclonal Antibody | anti-SELV antibody

SELV, CT (SELV, Selenoprotein V)

Cat. Num. AAA6003232

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SELV; Polyclonal Antibody; CT (SELV; Selenoprotein V); Anti -SELV; anti-SELV antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-SELV antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:50-100; Flow Cytometry: 1:10-50; Immunofluorescence: 1:10-50
• Immunogen: SELV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human SELV.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SELV Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SELV antibody detected the SELV protein (arrow).)

Immunohistochemistry (IHC)

(SELV Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SELV Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(SELV Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of SELV Antibody (C-term) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)

Related Product Information for anti-SELV antibody

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Product Categories/Family for anti-SELV antibody

Antibodies; Abs to Selenoprotein

NCBI and Uniprot Product Information

• NCBI GI #: 33186895
• NCBI GeneID: 348303
• NCBI Accession #: NP_874363.1
• NCBI GenBank Nucleotide #: NM_182704.1
• UniProt Accession #: P59797; Q17RG5
• Molecular Weight: 36,800 Da
• NCBI Official Full Name: selenoprotein V
• NCBI Official Symbol: SELV
• NCBI Protein Information: selenoprotein V
• UniProt Protein Name: Selenoprotein V
• Protein Family: Selenoprotein
• UniProt Gene Name: SELV
• UniProt Synonym Gene Names: SelV
• UniProt Entry Name: SELV_HUMAN

NCBI Description

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]

Uniprot Description

SELV: May be involved in a redox-related process (Potential). Belongs to the SelWTH family.

Chromosomal Location of Human Ortholog: 19q13.2

Molecular Function: selenium binding

Biological Process: cell redox homeostasis