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Knockout Validation (Knockout Validation: Lane 1: Wild-type A549 cell lysate; Lane 2: SCRN1 knockout A549 cell lysate; Predicted MW: 39~49kd Observed MW: 52kd Primary Ab: 1ug/ml Rabbit Anti-Human SCRN1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

Rabbit anti-Human Secernin 1 (SCRN1) Polyclonal Antibody | anti-SCRN1 antibody

Cy3-Linked Polyclonal Antibody to Secernin 1 (SCRN1)

Gene Names
SCRN1; SES1
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Secernin 1 (SCRN1); Polyclonal Antibody; Cy3-Linked Polyclonal Antibody to Secernin 1 (SCRN1); SES1; anti-SCRN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-SCRN1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
SCRN1 (Ala2~Lys414)
Conjugation
Cy3
Cross Reactivity
Human, Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2034024

Knockout Validation

(Knockout Validation: Lane 1: Wild-type A549 cell lysate; Lane 2: SCRN1 knockout A549 cell lysate; Predicted MW: 39~49kd Observed MW: 52kd Primary Ab: 1ug/ml Rabbit Anti-Human SCRN1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

Knockout Validation (Knockout Validation: Lane 1: Wild-type A549 cell lysate; Lane 2: SCRN1 knockout A549 cell lysate; Predicted MW: 39~49kd Observed MW: 52kd Primary Ab: 1ug/ml Rabbit Anti-Human SCRN1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
38,864 Da
NCBI Official Full Name
Secernin 1
NCBI Official Synonym Full Names
secernin 1
NCBI Official Symbol
SCRN1
NCBI Official Synonym Symbols
SES1
NCBI Protein Information
secernin-1
UniProt Protein Name
Secernin-1
Protein Family
UniProt Gene Name
SCRN1
UniProt Synonym Gene Names
KIAA0193

NCBI Description

This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

Uniprot Description

SCRN1: Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium. Belongs to the peptidase C69 family. Secernin subfamily.

Protein type: Nuclear envelope

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: nuclear membrane; nucleus

Molecular Function: protein binding

Biological Process: exocytosis

Research Articles on SCRN1

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Product Notes

The SCRN1 scrn1 (Catalog #AAA2068471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cy3-Linked Polyclonal Antibody to Secernin 1 (SCRN1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Secernin 1 (SCRN1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the SCRN1 scrn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Secernin 1 (SCRN1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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