Western Blot (WB)
((2ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat SEC23A Polyclonal Antibody | anti-SEC23A antibody
Goat anti-SEC23A Antibody
Western Blot: Approx 100kDa band observed in lysates of NIH3T3 (calculated MW of 86.2kDa according to Human NP_006355.2 and to Mouse NP_033173.2). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((2ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((2ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
Uniprot Description
SEC23A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A. Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q21.1
Cellular Component: COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; smooth endoplasmic reticulum membrane
Molecular Function: protein binding; zinc ion binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; intracellular protein transport; vesicle-mediated transport
Disease: Craniolenticulosutural Dysplasia
Research Articles on SEC23A
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Product Notes
The SEC23A sec23a (Catalog #AAA422056) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SEC23A Antibody reacts with Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Horse, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's SEC23A can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 100kDa band observed in lysates of NIH3T3 (calculated MW of 86.2kDa according to Human NP_006355.2 and to Mouse NP_033173.2). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the SEC23A sec23a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ANRAATTGHV ID. It is sometimes possible for the material contained within the vial of "SEC23A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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