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Western Blot (WB) (Western blot analysis of RTN4RL2 in rat brain tissue lysate with RTN4RL2 antibody at 1 μg/mL.)

Rabbit anti-Human RTN4RL2 Polyclonal Antibody | anti-RTN4RL2 antibody

RTN4RL2 Antibody

Gene Names
RTN4RL2; NgR2; NGRH1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
RTN4RL2 Antibody is affinity chromatography purified via peptide column.
Synonyms
RTN4RL2; Polyclonal Antibody; RTN4RL2 Antibody; NgR2; NGRH1; NGRL3; Reticulon-4 receptor-like 2; Nogo receptor-like 3; reticulon 4 receptor-like 2; anti-RTN4RL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.
Purity/Purification
RTN4RL2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
420
Applicable Applications for anti-RTN4RL2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2.
Buffer
RTN4RL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
RTN4RL2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of RTN4RL2 in rat brain tissue lysate with RTN4RL2 antibody at 1 μg/mL.)

Western Blot (WB) (Western blot analysis of RTN4RL2 in rat brain tissue lysate with RTN4RL2 antibody at 1 μg/mL.)
Related Product Information for anti-RTN4RL2 antibody
RTN4RL2 Antibody: Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 46 kDa
NCBI Official Full Name
reticulon-4 receptor-like 2
NCBI Official Synonym Full Names
reticulon 4 receptor-like 2
NCBI Official Symbol
RTN4RL2
NCBI Official Synonym Symbols
NgR2; NGRH1
NCBI Protein Information
reticulon-4 receptor-like 2; RTN4RL2; nogo receptor-like 3; Nogo-66 receptor homolog 1; nogo-66 receptor-related protein 2
UniProt Protein Name
Reticulon-4 receptor-like 2
Protein Family
UniProt Gene Name
RTN4RL2
UniProt Synonym Gene Names
NgR2
UniProt Entry Name
R4RL2_HUMAN

Uniprot Description

RTN4RL2: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Belongs to the Nogo receptor family.

Protein type: Cell development/differentiation; Receptor, misc.; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: cell surface; anchored to plasma membrane; external side of plasma membrane; lipid raft

Molecular Function: receptor activity

Biological Process: axon regeneration

Research Articles on RTN4RL2

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Product Notes

The RTN4RL2 rtn4rl2 (Catalog #AAA153580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RTN4RL2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RTN4RL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the RTN4RL2 rtn4rl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RTN4RL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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