Rabbit RRAS2 Polyclonal Antibody | anti-RRAS2 antibody

RRAS2 Antibody

Cat. Num. AAA9610156

• Gene Names: RRAS2; TC21
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: RRAS2; Polyclonal Antibody; RRAS2 Antibody; C86394; Oncogene RRAS2; Oncogene TC21; Ras like protein TC21; Ras related protein R Ras2; Ras-like protein TC21; Ras-related protein R-Ras2; Related RAS viral (r ras) oncogene homolog 2; Related RAS viral oncogene homolog 2; RRAS 2; RRAS2_HUMAN; TC 21; TC21; Teratocarcinoma oncogene; Teratocarcinoma oncogene TC21; anti-RRAS2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RRAS2 antibody detects endogenous levels of total RRAS2
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 127

• Applicable Applications for anti-RRAS2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000
• Immunogen: A synthesized peptide derived from human RRAS2
• Subcellular Location: Cell Membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
• Tissue Specificity: Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of RRAS2 using HuvEc whole cell lysates)

Related Product Information for anti-RRAS2 antibody

Function: It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Post-translational Modifications: May be post-translationally modified by both palmitoylation and polyisoprenylation.
Similarity: Belongs to the small GTPase superfamily. Ras family.

NCBI and Uniprot Product Information

• NCBI GI #: 156713451
• NCBI GeneID: 22800
• NCBI Accession #: NP_001096139.1
• NCBI GenBank Nucleotide #: NM_001102669.2
• UniProt Accession #: P62070; P17082; B2R9Z3; B7Z5Z2; B7Z6C4; B7Z7H6
• Molecular Weight: Observed: 23 kDa; Predicted: 24 kDa
• NCBI Official Full Name: ras-related protein R-Ras2 isoform b
• NCBI Official Synonym Full Names: RAS related 2
• NCBI Official Symbol: RRAS2
• NCBI Official Synonym Symbols: TC21
• NCBI Protein Information: ras-related protein R-Ras2
• UniProt Protein Name: Ras-related protein R-Ras2
• Protein Family: Ras-related protein
• UniProt Gene Name: RRAS2
• UniProt Synonym Gene Names: TC21

NCBI Description

This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Uniprot Description

It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.