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Western Blot (WB) (Western blotAll lanes: RPIA antibody IgG at 3.29ug/ml+ Mouse kidney tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 33 kDaObserved band size: 33 kDa)

Rabbit anti-Human, Mouse RPIA Polyclonal Antibody | anti-RPIA antibody

RPIA Antibody

Gene Names
RPIA; RPI; RPIAD
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
RPIA; Polyclonal Antibody; RPIA Antibody; Ribose-5-phosphate isomerase; Phosphoriboisomerase; RPI; anti-RPIA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
311
Applicable Applications for anti-RPIA antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Ribose-5-phosphate isomerase protein (C-230AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161204 / sc-161205
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: RPIA antibody IgG at 3.29ug/ml+ Mouse kidney tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 33 kDaObserved band size: 33 kDa)

Western Blot (WB) (Western blotAll lanes: RPIA antibody IgG at 3.29ug/ml+ Mouse kidney tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 33 kDaObserved band size: 33 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue MBS7045694 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissue MBS7045694 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer MBS7045694 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer MBS7045694 at dilution 1:100)
Related Product Information for anti-RPIA antibody
cytosol, ribose-5-phosphate isomerase activity, pentose-phosphate shunt

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,269 Da
NCBI Official Full Name
ribose-5-phosphate isomerase
NCBI Official Synonym Full Names
ribose 5-phosphate isomerase A
NCBI Official Symbol
RPIA
NCBI Official Synonym Symbols
RPI; RPIAD
NCBI Protein Information
ribose-5-phosphate isomerase
UniProt Protein Name
Ribose-5-phosphate isomerase
UniProt Gene Name
RPIA
UniProt Synonym Gene Names
RPI
UniProt Entry Name
RPIA_HUMAN

NCBI Description

The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]

Uniprot Description

RPIA: Defects in RPIA are the cause of ribose 5-phosphate isomerase deficiency (RPID). A patient has been described with a deficiency of ribose 5-phosphate isomerase who presented with leukoencephalopathy and peripheral neuropathy. Proton magnetic resonance spectroscopy of the brain revealed a highly elevated level of the polyols ribitol and D-arabitol, which were subsequently also found in high concentrations in body fluids. Deficient activity of RPIA, one of the pentose phosphate pathway enzymes, has been demonstrated in fibroblasts. Belongs to the ribose 5-phosphate isomerase family.

Protein type: Isomerase; EC 5.3.1.6; Carbohydrate Metabolism - pentose phosphate pathway

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: cytosol

Molecular Function: protein binding; ribose-5-phosphate isomerase activity

Biological Process: pentose-phosphate shunt

Disease: Ribose 5-phosphate Isomerase Deficiency

Research Articles on RPIA

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Product Notes

The RPIA rpia (Catalog #AAA7045694) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RPIA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RPIA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the RPIA rpia for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPIA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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