Structure
4-Methylbenzylidene camphor, Inhibitor
4-Methylbenzylidene camphor
Purity
99.59%
Synonyms
4-Methylbenzylidene camphor; 4-MBC; Enzacamene; inhibitor
Purity/Purification
99.59%
Form/Format
Solid. Powder
Solubility
DMSO: 47mg/mL (184.77mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H22O
SMILES
Cc1ccc(C=C2C(=O)C3(C)CCC2C3(C)C)cc1
CAS Number
36861-47-9
Target & IC50
AChE
In Vitro
4-Methylbenzylidene camphor has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation. In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for 4-Methylbenzylidene camphor, inhibitor
4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations,specifically UV B radiation, also has estrogenic activities.
Product Categories/Family for 4-Methylbenzylidene camphor, inhibitor
References
Stefan D, Kirsten M, Margret S, et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
Stefan D, Kirsten M, Margret S, et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.
Stefan D, Kirsten M, Margret S, et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.
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Product Notes
The 4-Methylbenzylidene camphor (Catalog #AAA5758358) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "4-Methylbenzylidene camphor, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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