Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit RP105/CD180 Polyclonal Antibody | anti-RP105/CD180 antibody
Anti-RP105/CD180 Antibody (Internal)
Gene Names
CD180; LY64; Ly78; RP105
Reactivity
HumanPredicted: Mouse, Monkey
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
RP105/CD180; Polyclonal Antibody; Anti-RP105/CD180 Antibody (Internal); Rabbit Polyclonal (IgG) to Human RP105/CD180; CD180; CD180 antigen; Lymphocyte antigen 64; Ly78; LY64; CD180 molecule; RP105; anti-RP105/CD180 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Monkey
Predicted: Mouse, Monkey
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CD180 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Sequence Length
661
Applicable Applications for anti-RP105/CD180 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human CD180.
Conjugation
Unconjugated
Epitope
Internal
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Aliquot to avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot analysis of CD180 expression in human spleen (A); mouse brain (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of CD180 expression in human spleen (A); mouse brain (B) whole cell lysates.)
Related Product Information for anti-RP105/CD180 antibody
CD180 is a cell surface molecule consisting of extracellularleucine-rich repeats (LRR) and a short cytoplasmic tail. the extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family ofpathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working inconcert with TLR4, controls B cell recognition and signaling oflipopolysaccharide (LPS), a membrane constituent of Gram-negativebacteria.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,179 Da
NCBI Official Full Name
CD180 antigen
NCBI Official Synonym Full Names
CD180 molecule
NCBI Official Symbol
CD180
NCBI Official Synonym Symbols
LY64; Ly78; RP105
NCBI Protein Information
CD180 antigen
UniProt Protein Name
CD180 antigen
UniProt Gene Name
CD180
UniProt Synonym Gene Names
LY64; RP105
NCBI Description
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
Uniprot Description
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells ().
Research Articles on RP105/CD180
Similar Products
Product Notes
The RP105/CD180 cd180 (Catalog #AAA2401583) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RP105/CD180 Antibody (Internal) reacts with Human Predicted: Mouse, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's RP105/CD180 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the RP105/CD180 cd180 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RP105/CD180, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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