Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human RNASE3 Polyclonal Antibody | anti-RNASE3 antibody
Anti-RNASE3 Antibody (aa123-151) IHC-plus
IHC-P (1:100)
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF)
(Confocal immunofluorescence of RNASE3 Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
Immunofluorescence (IF)
(Confocal immunofluorescence of RNASE3 Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
Western Blot (WB)
(Western blot of lysate from human spleen tissue lysate, using RNASE3 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.)
Western Blot (WB)
(Western blot of lysate from human spleen tissue lysate, using RNASE3 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.)
Western Blot (WB)
(RNASE3 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The RNASE3 antibody detected the RNASE3 protein (arrow).)
Western Blot (WB)
(RNASE3 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The RNASE3 antibody detected the RNASE3 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
Uniprot Description
RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family.
Protein type: EC 3.1.27.-; Secreted, signal peptide; Ribonuclease; Secreted
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: extracellular region; extracellular space
Molecular Function: endonuclease activity; nucleic acid binding; ribonuclease activity
Biological Process: antibacterial humoral response; defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process
Research Articles on RNASE3
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Product Notes
The RNASE3 rnase3 (Catalog #AAA2400290) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RNASE3 Antibody (aa123-151) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RNASE3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB). IF (1:10 - 1:50) IHC-P (1:100) WB (1:1000). Researchers should empirically determine the suitability of the RNASE3 rnase3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNASE3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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