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Western Blot (WB) (Western Blot: Sample: Rat Marrow Tissue.)

Rabbit anti-Human Ribonuclease A7 (RNASE7) Polyclonal Antibody | anti-RNASE7 antibody

Polyclonal Antibody to Ribonuclease A7 (RNASE7)

Gene Names
RNASE7; RAE1
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Ribonuclease A7 (RNASE7); Polyclonal Antibody; Polyclonal Antibody to Ribonuclease A7 (RNASE7); anti-RNASE7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against RNASE7. It has been selected for its ability to recognize RNASE7 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
0.96mg/ml (varies by lot)
Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSGSEF-KGMTSSQWFK IQHMQPSPQA CNSAMKNINK HTKRCKDLNT FLHEPFSSVA ATCQTPKIAC KNGDKNCHQS HGAVSLTMCK LTSGKHPNCR YKEKRQNKSY VVACKPPQKK DSQQFHLVPV HLDRV
Applicable Applications for anti-RNASE7 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant RNASE7 (Lys31~Val155) expressed in E.coli.
Cross Reactivity
Human, Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2070476
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Rat Marrow Tissue.)

Western Blot (WB) (Western Blot: Sample: Rat Marrow Tissue.)

Western Blot (WB)

(Western Blot: Sample: Recombinant RNASE7, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant RNASE7, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P. Samples: Human Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P. Samples: Human Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,419 Da
NCBI Official Full Name
ribonuclease 7
NCBI Official Synonym Full Names
ribonuclease A family member 7
NCBI Official Symbol
RNASE7
NCBI Official Synonym Symbols
RAE1
NCBI Protein Information
ribonuclease 7
UniProt Protein Name
Ribonuclease 7
Protein Family
UniProt Gene Name
RNASE7
UniProt Synonym Gene Names
RNase 7; SAP-2

NCBI Description

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

Uniprot Description

RNASE7: Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Belongs to the pancreatic ribonuclease family.

Protein type: EC 3.1.27.-; RNA-binding; Ribonuclease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytoplasm; extracellular region; extracellular space

Molecular Function: endonuclease activity; lipopolysaccharide binding; nucleic acid binding; peptidoglycan binding; ribonuclease activity

Biological Process: antibacterial humoral response; antimicrobial humoral response; defense response to fungus; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; innate immune response; membrane disruption in other organism

Research Articles on RNASE7

Similar Products

Product Notes

The RNASE7 rnase7 (Catalog #AAA2004301) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Ribonuclease A7 (RNASE7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ribonuclease A7 (RNASE7) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the RNASE7 rnase7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-KGMTSS QWFK IQHMQPSPQA CNSAMKNINK HTKRCKDLNT FLHEPFSSVA ATCQTPKIAC KNGDKNCHQS HGAVSLTMCK LTSGKHPNCR YKEKRQNKSY VVACKPPQKK DSQQFHLVPV HLDRV. It is sometimes possible for the material contained within the vial of "Ribonuclease A7 (RNASE7), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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