Western Blot (WB)
(Western blot analysis of RHBDD3 in rat lung tissue lysate with RHBDD3 antibody at 1 ug/mL.)
Rabbit RHBDD3 Polyclonal Antibody | anti-RHBDD3 antibody
RHBDD3 Antibody
Gene Names
RHBDD3; PTAG; C22orf3; HS984G1A
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
RHBDD3; Polyclonal Antibody; RHBDD3 Antibody; Rhomboid domain containing 3; pituitary tumor apoptosis gene; PTAG; anti-RHBDD3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
386
Applicable Applications for anti-RHBDD3 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the center of human RHBDD3.
Target Name
RHBDD3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of RHBDD3 in rat lung tissue lysate with RHBDD3 antibody at 1 ug/mL.)
Western Blot (WB)
(Western blot analysis of RHBDD3 in rat lung tissue lysate with RHBDD3 antibody at 1 ug/mL.)
Related Product Information for anti-RHBDD3 antibody
The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine, and apoptosis-inducing dopamine D2 analog, suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool. Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors, indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation.
Product Categories/Family for anti-RHBDD3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,484 Da
NCBI Official Full Name
rhomboid domain-containing protein 3
NCBI Official Synonym Full Names
rhomboid domain containing 3
NCBI Official Symbol
RHBDD3
NCBI Official Synonym Symbols
PTAG; C22orf3; HS984G1A
NCBI Protein Information
rhomboid domain-containing protein 3
UniProt Protein Name
Rhomboid domain-containing protein 3
Protein Family
UniProt Gene Name
RHBDD3
UniProt Synonym Gene Names
C22orf3
UniProt Entry Name
RHBD3_HUMAN
Uniprot Description
RHBDD3:
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: integral to membrane
Molecular Function: serine-type endopeptidase activity
Biological Process: response to xenobiotic stimulus; regulation of protein secretion; regulation of acute inflammatory response; negative regulation of natural killer cell activation; positive regulation of protein catabolic process; MAPKKK cascade; proteolysis; liver development
Research Articles on RHBDD3
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Product Notes
The RHBDD3 rhbdd3 (Catalog #AAA9401439) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RHBDD3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RHBDD3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the RHBDD3 rhbdd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHBDD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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