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Western Blot (WB) (Western blot analysis of Requiem in mouse kidney tissue lysate with Requiem antibody at 1 ug/mL.)

Rabbit anti-Human, Mouse REQUIEM Polyclonal Antibody | anti-REQUIEM antibody

REQUIEM Antibody

Gene Names
DPF2; REQ; UBID4; ubi-d4
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
REQUIEM; Polyclonal Antibody; REQUIEM Antibody; REQ; UBID4; ubi-d4; DPF2; double PHD fingers family 2; anti-REQUIEM antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Requiem antibody is predicted to not cross-react with other DPF protein family members.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
391
Applicable Applications for anti-REQUIEM antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the carboxy terminus of human Requiem.
Target Name
REQUIEM
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of Requiem in mouse kidney tissue lysate with Requiem antibody at 1 ug/mL.)

Western Blot (WB) (Western blot analysis of Requiem in mouse kidney tissue lysate with Requiem antibody at 1 ug/mL.)
Related Product Information for anti-REQUIEM antibody
Requiem is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It is expressed in numerous tissues in both cytosolic and nuclear regions and likely serves a regulatory role in rapid hematopoietic cell growth and turnover. Requiem has been found to act as an adaptor protein that links the NF-kB and SWI/SNF chromatin remodeling factor and is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
Product Categories/Family for anti-REQUIEM antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
23,599 Da
NCBI Official Full Name
requiem
NCBI Official Synonym Full Names
D4, zinc and double PHD fingers family 2
NCBI Official Symbol
DPF2
NCBI Official Synonym Symbols
REQ; UBID4; ubi-d4
NCBI Protein Information
zinc finger protein ubi-d4
UniProt Protein Name
Zinc finger protein ubi-d4
UniProt Gene Name
DPF2
UniProt Synonym Gene Names
BAF45D; REQ; UBID4; BAF45D
UniProt Entry Name
REQU_HUMAN

NCBI Description

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]

Uniprot Description

requiem: May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells. Belongs to the requiem/DPF family.

Protein type: Apoptosis; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: nucleoplasm; centrosome; intracellular membrane-bound organelle; cytoplasm; nuclear chromatin

Molecular Function: zinc ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis

Research Articles on REQUIEM

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Product Notes

The REQUIEM dpf2 (Catalog #AAA9413976) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REQUIEM Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's REQUIEM can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the REQUIEM dpf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REQUIEM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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