Rabbit anti-Mouse Rex-1/ZFP42 Polyclonal Antibody | anti-ZFP42 antibody

Anti-Rex-1/ZFP42 Antibody, Rabbit Polyclonal

Cat. Num. AAA8103755

• Gene Names: Zfp42; Rex1; Rex-1; Zfp-42
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Protein A & Antigen Affinity
• Synonyms: Rex-1/ZFP42; Polyclonal Antibody; Anti-Rex-1/ZFP42 Antibody; Rabbit Polyclonal; ZFP42 Antibody; Rabbit PAb; Antigen Affinity Purified; ZFP42 zinc finger protein; Anti-Rex-1 Antibody; Anti-Rex1 Antibody; Anti-Zfp-42 Antibody; anti-ZFP42 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Mouse ZFP42
• Purity/Purification: Protein A & Antigen Affinity
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-ZFP42 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Mouse ZFP42
• Conjugation: Unconjugated
• Preparation: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Mouse ZFP42, and purified by antigen affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Anti-ZFP42 rabbit polyclonal antibody at 1:500 dilution Lane A: Mouse brain tissue lysate Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 35kDa)

Related Product Information for anti-ZFP42 antibody

ZFP42, GeneID 132625, is a gene whose expression is closely associated with pluripotency/multipotency in both mouse and human embryonic stem cells. Loss of ZFP42 leads to impaired testicular function. Moreover, the functional connection of ZFP42 to genomic imprinting represents another case where newly made genes have co-evolved with lineage-specific phenomena.

NCBI and Uniprot Product Information

• NCBI GI #: 157057099
• NCBI GeneID: 22702
• NCBI Accession #: NP_033582.2
• NCBI GenBank Nucleotide #: NM_009556.3
• UniProt Accession #: P22227; Q4KMN3; Q7TPU3
• Molecular Weight: 32,398 Da
• NCBI Official Full Name: zinc finger protein 42
• NCBI Official Synonym Full Names: zinc finger protein 42
• NCBI Official Symbol: Zfp42
• NCBI Official Synonym Symbols: Rex1; Rex-1; Zfp-42
• NCBI Protein Information: zinc finger protein 42
• UniProt Protein Name: Zinc finger protein 42
• Protein Family: Zinc finger protein
• UniProt Gene Name: Zfp42
• UniProt Synonym Gene Names: Rex-1; Rex1; Zfp-42; REX-1; mREX-1

Uniprot Description

ZFP42: Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 8 A4|8 23.89 cM

Cellular Component: cytoplasm; nucleus; protein complex

Molecular Function: DNA binding; metal ion binding; nucleic acid binding; protein binding; sequence-specific DNA binding

Biological Process: in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; regulation of genetic imprinting; regulation of transcription, DNA-templated; spermatid development; transcription, DNA-dependent