Goat RER1 Polyclonal Antibody | anti-RER1 antibody

Goat Polyclonal to Human RER1

Cat. Num. AAA247638

• Reactivity: Gibbon, Gorilla, Human, Orangutan; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: RER1; Polyclonal Antibody; Goat Polyclonal to Human RER1; Anti-RER1 Antibody (C-Terminus) IHC-plus; Protein RER1; RP4-740C4.2; Human RER1; anti-RER1 antibody

• Host: Goat
• Reactivity: Gibbon, Gorilla, Human, Orangutan; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human RER1.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 196

• Applicable Applications for anti-RER1 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:128000), IHC-P (3.75 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic peptide C-HGKRRYRGKEDAGK from the C-terminus of human RER1 (NP_008964.3).
• Immunogen Type: Synthetic peptide
• Immunogen: RER1 antibody was raised against synthetic peptide C-HGKRRYRGKEDAGK from the C-terminus of human RER1 (NP_008964.3). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (93%); Mouse, Rat, Hamster, Panda, Bat, Bovine, Platypus, Catfish, Salmon (86%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-RER1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 116812591
• NCBI GeneID: 11079
• NCBI Accession #: NP_008964.3
• NCBI GenBank Nucleotide #: NM_007033.4
• UniProt Accession #: O15258; O95322
• Molecular Weight: 22,958 Da
• NCBI Official Full Name: protein RER1
• NCBI Official Synonym Full Names: retention in endoplasmic reticulum sorting receptor 1
• NCBI Official Symbol: RER1
• NCBI Protein Information: protein RER1; RER1 retention in endoplasmic reticulum 1 homolog
• UniProt Protein Name: Protein RER1
• Protein Family: Protein
• UniProt Gene Name: RER1
• UniProt Entry Name: RER1_HUMAN

NCBI Description

The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009]

Uniprot Description

RER1: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. Belongs to the RER1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: Golgi apparatus; cell surface; ER-Golgi intermediate compartment; integral to Golgi membrane

Molecular Function: acetylcholine receptor binding

Biological Process: retrograde vesicle-mediated transport, Golgi to ER