Immunohistochemistry (IHC)
(Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
Goat anti-Human PLA2G4A Polyclonal Antibody | anti-pla2g4a antibody
PLA2G4A, ID (Cytosolic Phospholipase A2, cPLA2, Phospholipase A2 Group IVA, CPLA2, PLA2G4)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: ELISA: 1:32,000
Western Blot: 1-3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
Immunohistochemistry (IHC)
(Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
Chemiluminescence
(PLA2G4A antibody (1ug/ml) staining of HeLa lysate (35ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Chemiluminescence
(PLA2G4A antibody (1ug/ml) staining of HeLa lysate (35ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response
By similarity.
Catalytic activity: Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Enzyme regulation: Stimulated by agonists such as ATP, EGF, thrombin and bradykinin as well as by cytosolic Ca2+
By similarity.
Subcellular location: Cytoplasm
By similarity. Cytoplasmic vesicle
By similarity. Note: Translocates to membrane vesicles in a calcium-dependent fashion
By similarity.
Domain: The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by presenting the active site to its substrate in response to elevations of cytosolic Ca2+
By similarity.
Sequence similarities: Contains 1 C2 domain.Contains 1 PLA2c domain.
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Product Notes
The pla2g4a pla2g4a (Catalog #AAA6011333) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The PLA2G4A, ID (Cytosolic Phospholipase A2, cPLA2, Phospholipase A2 Group IVA, CPLA2, PLA2G4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLA2G4A can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml. Researchers should empirically determine the suitability of the pla2g4a pla2g4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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