Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Rat Receptor II For The Fc Region Of Immunoglobulin G (FcgRII) Polyclonal Antibody | anti-FcgRII antibody
Polyclonal Antibody to Receptor II For The Fc Region Of Immunoglobulin G (FcgRII)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- IQVL KEDTVTLMCE GTHNTKNCST QWFHNGSSIW HQAQANYTFK ATVNDSGEYR CRMEETGISE PIHLGVISDW LLLQTSQLVF EEGETITLRC HSWKNKQLTK VLLFQNGKPV RYYHQSSNFS IPKANHSHSG NYYCKAYLGR TMHVSKPVTI TVQEPKSSSS LPVLTIVAAV AGIAVAAIVI ILVSLVYLKK
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
NCBI and Uniprot Product Information
Uniprot Description
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.
Protein type: Cell surface; Membrane protein, integral; Oncoprotein
Chromosomal Location of Human Ortholog: 13q24
Cellular Component: cell surface; dendritic spine; external side of plasma membrane; integral component of membrane; integral component of plasma membrane; membrane raft; plasma membrane; recycling endosome
Molecular Function: amyloid-beta binding; IgG binding; immunoglobulin binding; low affinity IgG receptor activity
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cell surface receptor signaling pathway; cerebellum development; defense response; dendrite development; endocytic recycling; immune complex clearance; immune response; immunoglobulin mediated immune response; mast cell activation; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of B cell proliferation; negative regulation of humoral immune response mediated by circulating immunoglobulin; negative regulation of immune response; negative regulation of immunoglobulin production; negative regulation of inflammatory response to antigenic stimulus; negative regulation of interleukin-10 production; negative regulation of neutrophil apoptosis; negative regulation of phagocytosis; negative regulation of type I hypersensitivity; phagocytosis, engulfment; positive regulation of JNK cascade; positive regulation of phagocytosis; positive regulation of transcription factor activity; receptor-mediated endocytosis; regulation of long-term neuronal synaptic plasticity; response to bacterium; response to estradiol
Research Articles on FcgRII
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Product Notes
The FcgRII fcgr2 (Catalog #AAA2016679) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Receptor II For The Fc Region Of Immunoglobulin G (FcgRII) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Receptor II For The Fc Region Of Immunoglobulin G (FcgRII) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the FcgRII fcgr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- IQVL KEDTVTLMCE GTHNTKNCST QWFHNGSSIW HQAQANYTFK ATVNDSGEYR CRMEETGISE PIHLGVISDW LLLQTSQLVF EEGETITLRC HSWKNKQLTK VLLFQNGKPV RYYHQSSNFS IPKANHSHSG NYYCKAYLGR TMHVSKPVTI TVQEPKSSSS LPVLTIVAAV AGIAVAAIVI ILVSLVYLKK. It is sometimes possible for the material contained within the vial of "Receptor II For The Fc Region Of Immunoglobulin G (FcgRII), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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