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Immunohistochemistry (IHC) (Immunochemical staining of rat FCGR2B in rat liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatic sinusoid. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Rabbit anti-Rat CD32B/Fcgr2b Polyclonal Antibody | anti-FCGR2B antibody

Anti-CD32B/Fcgr2b Antibody, Rabbit Polyclonal

Gene Names
Fcgr2b; CD32; FCRII; Fcgr2; FcgammaRIIB2
Reactivity
Rat
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
CD32B/Fcgr2b; Polyclonal Antibody; Anti-CD32B/Fcgr2b Antibody; Rabbit Polyclonal; CD32b/Fc gamma RIIB/FCGR2B Antibody; Rabbit PAb; Antigen Affinity Purified; Fc fragment of IgG; low affinity IIb; receptor (CD32); anti-FCGR2B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Rat CD32b/Fc gamma RIIB
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-FCGR2B antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:500-1:2000
Immunogen
Recombinant Rat CD32b/Fc gamma RIIB protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Rat CD32b/Fc gamma RIIB (rR CD32b/Fc gamma RIIB). CD32b/Fc gamma RIIB specific IgG was purified by Rat CD32b/Fc gamma RIIB affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining of rat FCGR2B in rat liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatic sinusoid. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Immunohistochemistry (IHC) (Immunochemical staining of rat FCGR2B in rat liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatic sinusoid. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Immunohistochemistry (IHC)

(Immunochemical staining of human FCGR2B in human kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC) (Immunochemical staining of human FCGR2B in human kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,048 Da
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-b
NCBI Official Synonym Full Names
Fc fragment of IgG, low affinity IIb, receptor
NCBI Official Symbol
Fcgr2b
NCBI Official Synonym Symbols
CD32; FCRII; Fcgr2; FcgammaRIIB2
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-b
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
UniProt Gene Name
Fcgr2
UniProt Synonym Gene Names
Fcgr2b; FcRII
UniProt Entry Name
FCGR2_RAT

Uniprot Description

FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.

Protein type: Oncoprotein; Cell surface; Membrane protein, integral

Cellular Component: cell surface; external side of plasma membrane; integral to membrane; lipid raft; plasma membrane; recycling endosome

Molecular Function: IgG binding; immunoglobulin binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cell surface receptor linked signal transduction; defense response; endocytic recycling; immune complex clearance; immune response; immunoglobulin mediated immune response; mast cell activation; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of B cell proliferation; negative regulation of humoral immune response mediated by circulating immunoglobulin; negative regulation of immune response; negative regulation of immunoglobulin production; negative regulation of inflammatory response to antigenic stimulus; negative regulation of interleukin-10 production; negative regulation of neutrophil apoptosis; negative regulation of phagocytosis; negative regulation of type I hypersensitivity; phagocytosis, engulfment; positive regulation of phagocytosis; receptor-mediated endocytosis; response to bacterium; response to estradiol stimulus

Research Articles on FCGR2B

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Product Notes

The FCGR2B fcgr2 (Catalog #AAA8112615) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD32B/Fcgr2b Antibody, Rabbit Polyclonal reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD32B/Fcgr2b can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the FCGR2B fcgr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD32B/Fcgr2b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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