Western Blot (WB)
(Western blot analysis of RBM3 Antibody (C-term) in Hela cell line lysates and mouse NIH-3T3 tissues lysates(35ug/lane). RBM3 (arrow) was detected using the purified Pab.)
Rabbit RBM3 Polyclonal Antibody | anti-RBM3 antibody
RBM3 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of RBM3 Antibody (C-term) in Hela cell line lysates and mouse NIH-3T3 tissues lysates(35ug/lane). RBM3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of RBM3 Antibody (C-term) in Hela cell line lysates and mouse NIH-3T3 tissues lysates(35ug/lane). RBM3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(RBM3 Antibody (C-term) (RB18777) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RBM3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(RBM3 Antibody (C-term) (RB18777) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RBM3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(RBM3 Antibody (C-term) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(RBM3 Antibody (C-term) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Sureban,S.M., Oncogene 27 (33), 4544-4556 (2008)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]
Uniprot Description
RBM3: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation.
Protein type: RNA processing; Translation; Ribosomal; RNA-binding
Chromosomal Location of Human Ortholog: Xp11.2
Cellular Component: cytoplasm; dendrite; nucleus; large ribosomal subunit
Molecular Function: protein binding; RNA binding; nucleotide binding; ribosomal large subunit binding
Biological Process: regulation of translation; RNA processing; miRNA-mediated gene silencing, production of miRNAs; translation; positive regulation of translation; response to cold
Research Articles on RBM3
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Product Notes
The RBM3 rbm3 (Catalog #AAA9209376) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 128-157. The RBM3 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's RBM3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the RBM3 rbm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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