Rabbit RAS Polyclonal Antibody | anti-RAS antibody

RAS Rabbit pAb

Cat. Num. AAA8543121

• Gene Names: NRAS; NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
• Purity: Affinity Chromatography
• Synonyms: RAS; Polyclonal Antibody; RAS Rabbit pAb; GTPase HRas; GTPase KRas; GTPase NRas; H-Ras-1; H-RASIDX; Ha-Ras; HAMSV; HRAS; K RAS2A; K RAS2B; K RAS4A; K RAS4B; K-RAS; KRAS; N-RAS; N-terminally processed; NRAS; p21ras; RASH1; RASK2; anti-RAS antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Chromatography
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
• Sequence Length: 189

• Applicable Applications for anti-RAS antibody: Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
• Application Notes: WB: 1:500-1:2000; ICC/IF: 1:50-1:200; IP: 1:50
• Immunogen: A synthesized peptide derived from human Ras
• Cellular Localization: Golgi Apparatus Membrane, Lipid-Anchor
• Preparation and Storage: Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

Related Product Information for anti-RAS antibody

The 21 kDa guanine-nucleotide binding proteins (K-Ras, H-Ras, and N-Ras) cycle between active (GTP-bound) and inactive (GDP-bound) forms. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

NCBI and Uniprot Product Information

• NCBI GI #: 4505451
• NCBI GeneID: 4893
• NCBI Accession #: NP_002515.1
• NCBI GenBank Nucleotide #: NP_002515.1
• UniProt Accession #: P01111; P01112; P01116
• Molecular Weight: 22kDa
• NCBI Official Full Name: GTPase NRas
• NCBI Official Synonym Full Names: NRAS proto-oncogene, GTPase
• NCBI Official Symbol: NRAS
• NCBI Official Synonym Symbols: NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
• NCBI Protein Information: GTPase NRas
• UniProt Protein Name: GTPase NRas
• Protein Family: Ras protein
• UniProt Gene Name: NRAS
• UniProt Synonym Gene Names: HRAS1
• UniProt Entry Name: RASN_HUMAN

NCBI Description

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]