Immunohistochemistry (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit RAPH1 Polyclonal Antibody | anti-RAPH1 antibody
Anti-RAPH1 Antibody (Internal)
Gene Names
RAPH1; LPD; RMO1; PREL2; PREL-2; ALS2CR9; ALS2CR18; RalGDS/AF-6
Reactivity
HumanPredicted: Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
RAPH1; Polyclonal Antibody; Anti-RAPH1 Antibody (Internal); Rabbit Polyclonal to Human RAPH1; anti-RAPH1 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of RAPH1 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Sequence Length
644
Applicable Applications for anti-RAPH1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human RAPH1.
Conjugation
Unconjugated
Epitope
Internal
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Aliquot to avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot analysis of RAPH1 expression in HepG2 (A); H9C2 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of RAPH1 expression in HepG2 (A); H9C2 (B) whole cell lysates.)
Related Product Information for anti-RAPH1 antibody
Mediator of localized membrane signals. Implicated in the regulation oflamellipodial dynamics. Negatively regulates cell adhesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72,874 Da
NCBI Official Full Name
ras-associated and pleckstrin homology domains-containing protein 1 isoform 3
NCBI Official Synonym Full Names
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
NCBI Official Symbol
RAPH1
NCBI Official Synonym Symbols
LPD; RMO1; PREL2; PREL-2; ALS2CR9; ALS2CR18; RalGDS/AF-6
NCBI Protein Information
ras-associated and pleckstrin homology domains-containing protein 1
UniProt Protein Name
Ras-associated and pleckstrin homology domains-containing protein 1
UniProt Gene Name
RAPH1
UniProt Synonym Gene Names
ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1; RAPH1; PREL-2
NCBI Description
This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Uniprot Description
Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
Research Articles on RAPH1
Similar Products
Product Notes
The RAPH1 raph1 (Catalog #AAA2401708) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RAPH1 Antibody (Internal) reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAPH1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the RAPH1 raph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAPH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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