Related Product Information for anti-RAD52 antibody
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.
Product Categories/Family for anti-RAD52 antibody
References
Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010). Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010). In press: Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010). Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010). Monsees, G.M., et al. Breast Cancer Res. Treat. (2010).
NCBI Description
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008]
Uniprot Description
RAD52: a protein involved in DNA double strand breaks and recombination. Associates with and is phosphorylated by c-Abl. Belongs to the RAD52/RAD22 family.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 12p13-p12.2
Cellular Component: nucleoplasm; nucleus
Molecular Function: identical protein binding; protein binding; DNA binding
Biological Process: DNA recombinase assembly; double-strand break repair; DNA repair; double-strand break repair via homologous recombination; DNA recombination
Product Notes
The RAD52 rad52 (Catalog #
AAA6340041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAD52, CT (RAD52, DNA repair protein RAD52 homolog) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAD52 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RAD52 rad52 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"RAD52, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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