Reactivity Chart
Goat Rab2 Polyclonal Antibody | anti-Rab2 antibody
Rab2 Pan Polyclonal Antibody
Reactivity Chart
Reactivity Chart
RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A has been shown to interact with GOLGA2.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex.
Subunit structure: Interacts with PRKCI. Ref.10
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor
Potential. Golgi apparatus membrane; Lipid-anchor
Potential. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Ref.11
Sequence similarities: Belongs to the small GTPase superfamily. Rab family.
Research Articles on Rab2
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Product Notes
The Rab2 rab2a (Catalog #AAA448028) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Rab2 Pan Polyclonal Antibody reacts with Human, mouse, rat, bovine, canine, chickevian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian and may cross-react with other species as described in the data sheet. AAA Biotech's Rab2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:250-1:2,000. Researchers should empirically determine the suitability of the Rab2 rab2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rab2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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