Western Blot (WB)
(mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS7604210 (SLCO4C1 Antibody) at dilution of 1:600)
Rabbit anti-Human, Mouse SLCO4C1 Polyclonal Antibody | anti-SLCO4C1 antibody
SLCO4C1 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Western Blot (WB)
(mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS7604210 (SLCO4C1 Antibody) at dilution of 1:600)
Western Blot (WB)
(mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS7604210 (SLCO4C1 Antibody) at dilution of 1:600)
NCBI and Uniprot Product Information
NCBI Description
SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLCO4C1: Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion- transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg. Belongs to the organo anion transporter (TC 2.A.60) family.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 5q21.2
Cellular Component: basolateral plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: sodium-independent organic anion transmembrane transporter activity
Biological Process: cell differentiation; multicellular organismal development; sodium-independent organic anion transport; spermatogenesis
Research Articles on SLCO4C1
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Product Notes
The SLCO4C1 slco4c1 (Catalog #AAA7604210) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLCO4C1 Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLCO4C1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SLCO4C1 slco4c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLCO4C1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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