Western Blot (WB)
(PTDSS2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PTDSS2 antibody detected the PTDSS2 protein (arrow).)
Rabbit anti-Human PTDSS2 Polyclonal Antibody | anti-PTDSS2 antibody
PTDSS2 Antibody (N-term)
IHC-P~~1:10~50
Western Blot (WB)
(PTDSS2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PTDSS2 antibody detected the PTDSS2 protein (arrow).)
Western Blot (WB)
(PTDSS2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PTDSS2 antibody detected the PTDSS2 protein (arrow).)
Immunohistochemistry (IHC)
(PTDSS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTDSS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(PTDSS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTDSS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
membrane phospholipids. In addition to its role as a structural
component, PS is involved in cell signaling, blood coagulation, and
apoptosis. PS is synthesized by a calcium-dependent base-exchange
reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that
exchange L-serine for the polar head group of phosphatidylcholine
(PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al.,
2001 [PubMed 11084049]).
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Grandmaison, P.A., et al. Biochim. Biophys. Acta 1636(1):1-11(2004)
Sturbois-Balcerzak, B., et al. J. Biol. Chem. 276(11):8205-8212(2001)
NCBI and Uniprot Product Information
NCBI Description
Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009]
Uniprot Description
PTDSS2: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Belongs to the phosphatidyl serine synthase family.
Protein type: Lipid Metabolism - glycerophospholipid; EC 2.7.8.29; Membrane protein, multi-pass; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane
Molecular Function: CDP-diacylglycerol-serine O-phosphatidyltransferase activity
Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine biosynthetic process
Research Articles on PTDSS2
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Product Notes
The PTDSS2 ptdss2 (Catalog #AAA9201929) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The PTDSS2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTDSS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000 IHC-P~~1:10~50. Researchers should empirically determine the suitability of the PTDSS2 ptdss2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTDSS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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