Rabbit anti-Human, Mouse PRSS16 Polyclonal Antibody | anti-PRSS16 antibody

PRSS16, NT (PRSS16, TSSP, Thymus-specific serine protease, Serine protease 16)

Cat. Num. AAA647941

• Gene Names: PRSS16; TSSP
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: PRSS16; Polyclonal Antibody; NT (PRSS16; TSSP; Thymus-specific serine protease; Serine protease 16); Anti -PRSS16; anti-PRSS16 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-PRSS16 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: PRSS16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human PRSS16.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PRSS16 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PRSS16 antibody detected the PRSS16 protein (arrow).)

Western Blot (WB)

(PRSS16 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PRSS16 antibody detected the PRSS16 protein (arrow).)

Related Product Information for anti-PRSS16 antibody

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.

Product Categories/Family for anti-PRSS16 antibody

Antibodies; Abs to Enzymes; Protease (Proteinase; Peptidase)

NCBI and Uniprot Product Information

• NCBI GI #: 530381338
• NCBI GeneID: 10279
• NCBI Accession #: XP_005248845.1
• NCBI GenBank Nucleotide #: XM_005248788.1
• UniProt Accession #: Q9NQE7; O75416
• Molecular Weight: 55,049 Da
• NCBI Official Full Name: thymus-specific serine protease isoform X1
• NCBI Official Synonym Full Names: protease, serine, 16 (thymus)
• NCBI Official Symbol: PRSS16
• NCBI Official Synonym Symbols: TSSP
• NCBI Protein Information: thymus-specific serine protease; serine protease 16; thymus specific serine peptidase
• UniProt Protein Name: Thymus-specific serine protease
• Protein Family: Thymus-specific serine protease
• UniProt Gene Name: PRSS16
• UniProt Synonym Gene Names: TSSP
• UniProt Entry Name: TSSP_HUMAN

NCBI Description

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Protease that may play a role in T-cell development.

Subcellular location: Cytoplasmic vesicle. Note: Vesicular, either lysosomal or endosomal.

Tissue specificity: Expressed predominantly in cortical thymic epithelial cells.

Developmental stage: Expressed in fetal thymus.

Sequence similarities: Belongs to the peptidase S28 family.

Sequence caution: The sequence CAB94769.1 differs from that shown. Reason: Erroneous gene model prediction.