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Western Blot (WB) (Western Blot: Sample: Human A549 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse PTPRZ Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Rabbit anti-Mouse Protein Tyrosine Phosphatase Receptor Type Z Polyclonal Antibody | anti-PTPRZ antibody

Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ)

Gene Names
Ptprz1; Ptpz; Ptprz; RPTPz; PTPbeta; PTPzeta; AI850339; DSD-1-PG; Rptpbeta; R-PTP-zeta
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Protein Tyrosine Phosphatase Receptor Type Z; Polyclonal Antibody; Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ); PTPRZ1; HPTPZ; HPTPzeta; PTP18; PTPR-Z; PTPZ; RPTPB; RPTPbeta; Phosphacan; Receptor-type tyrosine-protein phosphatase zeta; anti-PTPRZ antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against PTPRZ. It has been selected for its ability to recognize PTPRZ in immunohistochemical staining and western blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, Containing 0.02% NaN3, 50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence Length
2314
Applicable Applications for anti-PTPRZ antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-1:5000
Fragment
PTPRZ (Leu32~Phe163)
Conjugate
No Conjugate
Cross Reactivity
Human, Mouse
Immunoglobulin Type
IgG
Quality Control
Content: The quality control contains recombinant PTPRZ (Leu32~Phe163) disposed in loading buffer.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control. Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2072057
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Human A549 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse PTPRZ Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Western Blot (WB) (Western Blot: Sample: Human A549 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse PTPRZ Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Western Blot (WB)

(Western Blot: Sample: Recombinant protein.)

Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin- embedded brain tissue))

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded brain tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
254,405 Da
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase zeta isoform 3
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type Z, polypeptide 1
NCBI Official Symbol
Ptprz1
NCBI Official Synonym Symbols
Ptpz; Ptprz; RPTPz; PTPbeta; PTPzeta; AI850339; DSD-1-PG; Rptpbeta; R-PTP-zeta
NCBI Protein Information
receptor-type tyrosine-protein phosphatase zeta
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase zeta
UniProt Gene Name
Ptprz1
UniProt Synonym Gene Names
R-PTP-zeta

Uniprot Description

PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 6|6 A3.1

Cellular Component: axon; cell soma; cytoplasm; dendrite; dendritic spine; extracellular region; extracellular space; filopodium; growth cone; integral component of membrane; intrinsic component of plasma membrane; lamellipodium; membrane; plasma membrane; postsynaptic membrane; proteinaceous extracellular matrix

Molecular Function: fibroblast growth factor binding; hydrolase activity; phosphoprotein phosphatase activity; phosphoric monoester hydrolase activity; protein binding; protein tyrosine phosphatase activity

Biological Process: axonal fasciculation; axonogenesis; dephosphorylation; hemopoietic progenitor cell differentiation; learning and/or memory; negative regulation of cell proliferation; oligodendrocyte differentiation; positive regulation of cell migration; positive regulation of fibroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; protein amino acid dephosphorylation; regulation of dendrite morphogenesis

Research Articles on PTPRZ

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Product Notes

The PTPRZ ptprz1 (Catalog #AAA2033721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Tyrosine Phosphatase Receptor Type Z can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-1:5000. Researchers should empirically determine the suitability of the PTPRZ ptprz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Tyrosine Phosphatase Receptor Type Z, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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