Rabbit anti-Human, Rat Proline Transporter Polyclonal Antibody | anti-opuE antibody
Proline Transporter
Reactivity
Human, Rat
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
Proline Transporter; Polyclonal Antibody; Anti -Proline Transporter; anti-opuE antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat Proline Transporter. Species Crossreactivity: human
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide
Applicable Applications for anti-opuE antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:100,000 using 50-100ng control peptide per well.
Western Blot: 1:1000-1:5000 (ECL). Recognize a ~68kD band in rat and human brain. Deglycosylation reduces the MW to ~53kD.
Dilution: ELISA: 1:100,000 using 50-100ng control peptide per well.
Western Blot: 1:1000-1:5000 (ECL). Recognize a ~68kD band in rat and human brain. Deglycosylation reduces the MW to ~53kD.
Immunogen
A synthetic peptide corresponding to 24aa, near the C-terminal, cytoplasmic domain of rat Proline Transporter, conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-opuE antibody
The regulated exocytotic release of neurotransmitters in response to neural activity requires storage within intracellular vesicles. In the nervous system, these vesicles are the synaptic vesicles that are derived from the endosomal compartment, whereas in endocrine cells larger secretory granules, such as the chromaffin granules of adrenal medulla, are derived from the trans golgi networks. For classical transmitters that are synthesized in the cytoplasm or appear there after removal form the synapses by plasma membrane reuptake, storage depends upon the active transport into the vesicles. Several distinct transport activities have been identified for monoamines, acetylcholine, glutamate, GABA and glycine. Vesicular monoamine transporters (VMATs) catalyze transport and storage of monoamines, serotonin, dopamine, norepinephrine, epinephrine, and histamine. The driving force utilized by the VMAT is the H+ electrochemical gradient generated by a vacuolar ATP-dependent H+ pump (V-ATPase) located on vesicular plasma membrane. VMAT is inhibited by a wide variety of compounds including reserpine and tetrabenazine. In contrast to the plasma membrane transporters for dopamine, norepinephrine, and 5-HT which show relative substrate specificity, the monoamine transporter recognizes various monoamine with similar affinity. It was therefore speculated that either similar or identical transporters mediate the monoamine transport in all the tissues. Rat Proline transporter is a high affinity sodium and chloride dependent L-Proline transporter. It is a 661aa, ~68-kD protein with 12 transmembrane domain.
Product Categories/Family for anti-opuE antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
proline transporter
NCBI Official Symbol
opuE
NCBI Protein Information
proline transporter
Protein Family
Similar Products
Product Notes
The opuE (Catalog #AAA613695) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Proline Transporter reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Proline Transporter can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:100,000 using 50-100ng control peptide per well. Western Blot: 1:1000-1:5000 (ECL). Recognize a ~68kD band in rat and human brain. Deglycosylation reduces the MW to ~53kD. Researchers should empirically determine the suitability of the opuE for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Proline Transporter, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
