Rabbit anti-Rat Progesterone Receptor (PGR) Polyclonal Antibody | anti-PGR antibody
Polyclonal Antibody to Progesterone Receptor (PGR)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QLVPPLINL LMSIEPDVVY AGHDNTKPDT SSSLLTSLNQ LGERQLLSVV KWSKSLPGFR NLHIDDQITL IQYSWMSLMV
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
NCBI and Uniprot Product Information
NCBI Description
receptor for progesterone; regulates glutamic acid decarboxylase expression in the hypothalamus during proestrus; may mediate production of the GnRH and LH surge [RGD, Feb 2006]
Uniprot Description
PR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 8q11
Cellular Component: axon; axon terminus; cytoplasm; cytosol; dendrite; dendritic spine; endoplasmic reticulum; mitochondrion; neuron projection; nucleus; perikaryon; plasma membrane
Molecular Function: ATPase binding; DNA binding transcription factor activity; enzyme binding; hormone binding; ligand-dependent nuclear receptor activity; protein binding; receptor binding; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; zinc ion binding
Biological Process: alveolus development; diterpenoid metabolic process; epithelial cell maturation; female mating behavior; luteinization; mammary gland development; negative regulation of apoptosis; negative regulation of transcription, DNA-dependent; ovulation from ovarian follicle; positive regulation of cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; progesterone receptor signaling pathway; regulation of epithelial cell proliferation; regulation of transcription, DNA-templated; response to cocaine; response to estrogen; response to progesterone; steroid hormone mediated signaling; transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on PGR
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Product Notes
The PGR pgr (Catalog #AAA2015154) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Progesterone Receptor (PGR) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Progesterone Receptor (PGR) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PGR pgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QLVPPLINL LMSIEPDVVY AGHDNTKPDT SSSLLTSLNQ LGERQLLSVV KWSKSLPGFR NLHIDDQITL IQYSWMSLMV. It is sometimes possible for the material contained within the vial of "Progesterone Receptor (PGR), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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