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Western Blot (WB) (Western Blot: Sample: Recombinant PCT, Rat.)

Rabbit anti-Rat Procalcitonin Polyclonal Antibody | anti-PCT antibody

Polyclonal Antibody to Procalcitonin (PCT)

Gene Names
Calca; CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin
Reactivity
Rat
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Procalcitonin; Polyclonal Antibody; Polyclonal Antibody to Procalcitonin (PCT); anti-PCT antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against PCT. It has beenselected for its ability to recognize PCT in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Applicable Applications for anti-PCT antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Fragment
PCT (Val26~Asn136)
Organism Species
Rattus norvegicus (Rat)
Cross Reactivity
Rat
Conjugate
No Conjugate
Immunogen
Recombinant PCT (Val26~Asn136) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2046076
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant PCT, Rat.)

Western Blot (WB) (Western Blot: Sample: Recombinant PCT, Rat.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Rat Testis Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Rat Testis Tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,948 Da
NCBI Official Full Name
calcitonin gene-related peptide 1 isoform Calca preproprotein
NCBI Official Synonym Full Names
calcitonin-related polypeptide alpha
NCBI Official Symbol
Calca
NCBI Official Synonym Symbols
CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin
NCBI Protein Information
calcitonin gene-related peptide 1
UniProt Protein Name
Calcitonin
UniProt Gene Name
Calca
UniProt Synonym Gene Names
Calc

NCBI Description

an inhibitor of lactotroph function and a potent vasodilator [RGD, Feb 2006]

Uniprot Description

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q35

Cellular Component: axon; cell soma; cytoplasm; extracellular region; extracellular space; intracellular; neuron projection; nucleus; terminal bouton

Molecular Function: calcitonin receptor binding; hormone activity; identical protein binding; neuropeptide hormone activity; protein complex binding; receptor binding

Biological Process: activation of protein kinase activity; adenylate cyclase activation; adenylate cyclase-activating G-protein coupled receptor signaling pathway; aging; cellular calcium ion homeostasis; detection of temperature stimulus involved in sensory perception of pain; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); embryo implantation; endothelial cell migration; endothelial cell proliferation; feeding behavior; G-protein coupled receptor internalization; inflammatory response; leukocyte adhesion; monocyte chemotaxis; negative regulation of blood pressure; negative regulation of bone resorption; negative regulation of neurological process; negative regulation of ossification; negative regulation of osteoclast differentiation; negative regulation of smooth muscle contraction; negative regulation of transcription, DNA-dependent; neurological system process involved in regulation of systemic arterial blood pressure; neuromuscular junction development; neuropeptide signaling pathway; positive regulation of adenylate cyclase activity; positive regulation of cAMP biosynthetic process; positive regulation of cAMP metabolic process; positive regulation of cell adhesion; positive regulation of interleukin-1 alpha production; positive regulation of interleukin-8 production; positive regulation of macrophage differentiation; positive regulation of ossification; protein amino acid phosphorylation; receptor internalization; regulation of blood pressure; regulation of cytosolic calcium ion concentration; regulation of heart contraction; regulation of heart rate; response to heat; response to pain; vasculature development; vasodilation; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure

Research Articles on PCT

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Product Notes

The PCT calca (Catalog #AAA2026771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Procalcitonin (PCT) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Procalcitonin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PCT calca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Procalcitonin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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