Rabbit anti-Rat Procalcitonin Polyclonal Antibody | anti-PCT antibody
Polyclonal Antibody to Procalcitonin (PCT)
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
NCBI and Uniprot Product Information
NCBI Description
an inhibitor of lactotroph function and a potent vasodilator [RGD, Feb 2006]
Uniprot Description
CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q35
Cellular Component: axon; cell soma; cytoplasm; extracellular region; extracellular space; intracellular; neuron projection; nucleus; terminal bouton
Molecular Function: calcitonin receptor binding; hormone activity; identical protein binding; neuropeptide hormone activity; protein complex binding; receptor binding
Biological Process: activation of protein kinase activity; adenylate cyclase activation; adenylate cyclase-activating G-protein coupled receptor signaling pathway; aging; cellular calcium ion homeostasis; detection of temperature stimulus involved in sensory perception of pain; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); embryo implantation; endothelial cell migration; endothelial cell proliferation; feeding behavior; G-protein coupled receptor internalization; inflammatory response; leukocyte adhesion; monocyte chemotaxis; negative regulation of blood pressure; negative regulation of bone resorption; negative regulation of neurological process; negative regulation of ossification; negative regulation of osteoclast differentiation; negative regulation of smooth muscle contraction; negative regulation of transcription, DNA-dependent; neurological system process involved in regulation of systemic arterial blood pressure; neuromuscular junction development; neuropeptide signaling pathway; positive regulation of adenylate cyclase activity; positive regulation of cAMP biosynthetic process; positive regulation of cAMP metabolic process; positive regulation of cell adhesion; positive regulation of interleukin-1 alpha production; positive regulation of interleukin-8 production; positive regulation of macrophage differentiation; positive regulation of ossification; protein amino acid phosphorylation; receptor internalization; regulation of blood pressure; regulation of cytosolic calcium ion concentration; regulation of heart contraction; regulation of heart rate; response to heat; response to pain; vasculature development; vasodilation; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure
Research Articles on PCT
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Product Notes
The PCT calca (Catalog #AAA2026771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Procalcitonin (PCT) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Procalcitonin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PCT calca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Procalcitonin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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