Rabbit anti-Human PRICKLE2 Polyclonal Antibody | anti-PRICKLE2 antibody

PRICKLE2 Antibody

Cat. Num. AAA7045842

• Gene Names: PRICKLE2; EPM5
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: PRICKLE2; Polyclonal Antibody; PRICKLE2 Antibody; Prickle-like protein 2; anti-PRICKLE2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 844

• Applicable Applications for anti-PRICKLE2 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC: 1:20-1:200
• Species: Human
• Immunogen: Recombinant human Prickle-like protein 2 protein (C-230AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-69230 / sc-69231 / sc-69232 / sc-292448
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045842 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7045842 at dilution 1:100)

Related Product Information for anti-PRICKLE2 antibody

cytoplasm, Wnt signaling pathway, planar cell polarity pathway

NCBI and Uniprot Product Information

• NCBI GI #: 38524620
• NCBI GeneID: 166336
• NCBI Accession #: NP_942559.1
• NCBI GenBank Nucleotide #: NM_198859.3
• UniProt Accession #: Q7Z3G6; Q0VF44
• Molecular Weight: 95,615 Da
• NCBI Official Full Name: prickle-like protein 2
• NCBI Official Synonym Full Names: prickle planar cell polarity protein 2
• NCBI Official Symbol: PRICKLE2
• NCBI Official Synonym Symbols: EPM5
• NCBI Protein Information: prickle-like protein 2
• UniProt Protein Name: Prickle-like protein 2
• Protein Family: Prickle-like protein
• UniProt Gene Name: PRICKLE2
• UniProt Entry Name: PRIC2_HUMAN

NCBI Description

This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]

Uniprot Description

PRICKLE2: Defects in PRICKLE2 are the cause of progressive myoclonic epilepsy type 5 (EPM5). EPM5 is a neurodegenerative disorder characterized by myoclonic seizures and variable neurologic symptoms including cognitive decline and persistent movement abnormalities. Belongs to the prickle / espinas / testin family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: cytoplasm

Disease: Epilepsy, Progressive Myoclonic 5