Western Blot (WB)
(Western blot analysis of hPPP3CC-E33 in HL-60, Jurkat, A375 cell line lysates (35ug/lane). PPP3CC (arrow) was detected using the purified Pab.)
Rabbit anti-Human PPP3CC Polyclonal Antibody | anti-PPP3CC antibody
PPP3CC Antibody (N-term)
Western Blot (WB)
(Western blot analysis of hPPP3CC-E33 in HL-60, Jurkat, A375 cell line lysates (35ug/lane). PPP3CC (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of hPPP3CC-E33 in HL-60, Jurkat, A375 cell line lysates (35ug/lane). PPP3CC (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Gerber, D.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(15):8993-8998 (2003).
Bennasser, Y., et al., Virology 303(1):174-180 (2002).
Esau, C., et al., J. Exp. Med. 194(10):1449-1459 (2001).
Muramatsu, T., et al., Biochem. Biophys. Res. Commun. 188(1):265-271 (1992).
NCBI and Uniprot Product Information
NCBI Description
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
PPP3CC: a calmodulin-dependent Ser/Thr phosphatase also known as calcineurin A gamma. Involved in a wide range of biologic activities, acting as a Ca(2 )-dependent modifier of phosphorylation status. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively.
Protein type: EC 3.1.3.16; Motility/polarity/chemotaxis; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 8p21.3
Cellular Component: cytosol
Molecular Function: calmodulin binding; metal ion binding; phosphoprotein phosphatase activity
Biological Process: dephosphorylation; apoptosis
Research Articles on PPP3CC
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Product Notes
The PPP3CC ppp3cc (Catalog #AAA9208287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-47. The PPP3CC Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPP3CC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the PPP3CC ppp3cc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP3CC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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