Rabbit anti-Human, Mouse PPIP5K2 Polyclonal Antibody | anti-PPIP5K2 antibody
PPIP5K2 Antibody
Gene Names
PPIP5K2; VIP2; IP7K2; HISPPD1
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PPIP5K2; Polyclonal Antibody; PPIP5K2 Antibody; Diphosphoinositol pentakisphosphate kinase 2; HISPPD1; Histidine acid phosphatase domain containing 1; Histidine acid phosphatase domain containing protein 1; Histidine acid phosphatase domain-containing protein 1; hsVIP2; Inositol heptaphosphate kinase 2; Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; InsP6 and PP IP5 kinase 2; InsP6 and PP-IP5 kinase 2; IP7K2; PP IP5 kinase 2; Ppip5k2; VIP1 homolog 2; VIP2; VIP2_HUMAN; anti-PPIP5K2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PPIP5K2 Antibody detects endogenous levels of PPIP5K2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PPIP5K2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PPIP5K2.
Conjugation
Unconjugated
Similarity
The C-terminal acid phosphatase-like domain binds PtdIns(3, 4, 5)P3 and InsP6. Despite its similarity with the phosphatase domain of histidine acid phosphatases, it has no phosphatase activity. Belongs to the histidine acid phosphatase family. VIP1 subfamily.
Function
Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4. Required for normal hearing.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
138,106 Da
NCBI Official Full Name
inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 2
NCBI Official Synonym Full Names
diphosphoinositol pentakisphosphate kinase 2
NCBI Official Symbol
PPIP5K2
NCBI Official Synonym Symbols
VIP2; IP7K2; HISPPD1
NCBI Protein Information
inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; VIP1 homolog 2; histidine acid phosphatase domain-containing protein 1; inositol heptaphosphate kinase 2; insP6 and PP-IP5 kinase 2
UniProt Protein Name
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
UniProt Gene Name
PPIP5K2
UniProt Synonym Gene Names
HISPPD1; KIAA0433; VIP2; hsVIP2
UniProt Entry Name
VIP2_HUMAN
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Product Notes
The PPIP5K2 ppip5k2 (Catalog #AAA9630628) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPIP5K2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PPIP5K2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PPIP5K2 ppip5k2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPIP5K2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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