Rabbit polycystic kidney disease 2-like 1 Polyclonal Antibody | anti-PKD2L1 antibody
Rabbit anti-human polycystic kidney disease 2-like 1 polyclonal Antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Uniprot Description
PKD2L1: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling. Belongs to the polycystin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Motility/polarity/chemotaxis; Membrane protein, integral; Channel, cation
Chromosomal Location of Human Ortholog: 10q24
Cellular Component: cell surface; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; nonmotile primary cilium; integral to membrane; plasma membrane; receptor complex
Molecular Function: identical protein binding; sour taste receptor activity; protein binding; calcium-activated potassium channel activity; cation transmembrane transporter activity; calcium channel activity; cytoskeletal protein binding; cation channel activity; calcium ion binding; alpha-actinin binding; sodium channel activity; muscle alpha-actinin binding; calcium activated cation channel activity
Biological Process: smoothened signaling pathway; detection of mechanical stimulus; sensory perception of sour taste; detection of chemical stimulus involved in sensory perception of sour taste; cation transport
Research Articles on PKD2L1
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Product Notes
The PKD2L1 pkd2l1 (Catalog #AAA710924) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human polycystic kidney disease 2-like 1 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's polycystic kidney disease 2-like 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the PKD2L1 pkd2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "polycystic kidney disease 2-like 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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