Structure
JMV 2959 Biochemical
JMV 2959
Purity
>98% (HPLC)
Synonyms
JMV 2959; JMV2959; JMV-2959; JMV 2959 biochemical
Purity/Purification
>98% (HPLC)
Suitability
Soluble in DMSO
Target
GHS-R
Receptor
IC50: 32nM (GHS-R1a)
Chemical Name
N-[(R)-1-[4-(4-Methoxybenzyl)-5-phenethyl-4H-124-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2-aminoacetamide
SMILES
O=C(N[C@@H](C1=NN=C(CCC2=CC=CC=C2)N1CC3=CC=C(OC)C=C3)CC4=CNC5=C4C=CC=C5)CN
Molecular Formula
C??H??N?O?
CAS Number
925238-89-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for JMV 2959 biochemical
JMV 2959 is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32nM.
Product Categories/Family for JMV 2959 biochemical
References
1. Moulin A et al. The 124-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959 a potent antagonist. Amino Acids. 2013 Feb; 44 (2):301-14.
2. Engel JA et al. Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates thenMDAR antagonist phencyclidine-induced impairments in prepulse inhibition. Psychopharmacology (Berl). 2015 Dec; 232 (23):4285-92.
3. Clifford PS et al. Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors. Addict Biol. 2012 Nov; 17 (6):956-63.
2. Engel JA et al. Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates thenMDAR antagonist phencyclidine-induced impairments in prepulse inhibition. Psychopharmacology (Berl). 2015 Dec; 232 (23):4285-92.
3. Clifford PS et al. Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors. Addict Biol. 2012 Nov; 17 (6):956-63.
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Product Notes
The JMV 2959 (Catalog #AAA3609373) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "JMV 2959, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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